HOT ! LEVEL 3 – pH OPTIMUM RETINOL REPAIRING - 5000 IUs

Formulated For

Moderate to advanced wrinkles, irregular texture, visible photoaging. Your skin has adapted to lower retinol concentrations and is ready for deeper dermal remodeling. This is the concentration used in our clinical study.

The Mechanism

At 5,000 IUs, Level 3 drives remodeling at the reticular dermal level — where the structural collagen networks that determine skin firmness and wrinkle depth are built. Full spectrum nuclear receptor binding (RAR-α, RAR-β, RAR-γ) activates comprehensive gene modulation: collagen and elastin regeneration, MMP suppression, and accelerated keratinocyte turnover. The AP-1 pathway is simultaneously inhibited — reducing collagen destruction while increasing collagen production. This is the dual mechanism that makes retinol one of the only topical ingredients with evidence of direct gene-level skin remodeling.

Clinical Results

Independent 12-week clinical study, 33 women ages 40–65: 97% reported improvement in fine lines and wrinkles. 94% reported improved elasticity. 91% reported improved firmness. 97% reported no significant sensitivity. Unretouched photos.

How To Use

Apply nightly to clean skin. Expect a 2–4 week adjustment period — this is evidence that the retinoid cascade is fully activating. Pair with THD-Ascorbate Vitamin C Serum: retinol drives collagen transcription, THD-Ascorbate delivers the cofactor for prolyl hydroxylase to stabilize that collagen. Broad-spectrum SPF 30+ required daily.

Ingredients

Purified Water, Niacinamide, Squalane, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Sclerocarya Birrea Seed Oil, Caprylic/Capric Triglyceride, Hexylresorcinol, Retinol, Ceramide NP, Sodium Hyaluronate, Phytosterols, Aloe Barbadensis Leaf Extract, Dimethicone, Cocos Nucifera (Coconut) Oil, Tocopheryl Acetate, Persea Gratissima (Avocado) Oil, Ethyl Linoleate, Mica, Olea Europaea (Olive) Fruit Oil, Cetearyl Alcohol, Disodium EDTA, Phenoxyethanol, Sodium Polyacrylate, Polysorbate 20, Ethylhexylglycerin, Stearic Acid